SciTegic07090714152D 11 11 0 0 0 0 999 V2000 1.2990 -0.7500 0.0000 C 0 0 1.2990 0.7500 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 2.5973 -1.5031 0.0000 C 0 0 0.0000 1.5000 0.0000 C 0 0 2.5956 -2.7031 0.0000 O 0 0 -1.2990 0.7500 0.0000 C 0 0 -1.2990 -0.7500 0.0000 C 0 0 -2.3383 1.3500 0.0000 O 0 0 2.3383 1.3500 0.0000 C 0 0 3.6375 -0.9049 0.0000 C 0 0 2 1 1 0 3 1 2 0 4 1 1 0 5 2 2 0 6 4 2 0 7 8 2 0 8 3 1 0 9 7 1 0 10 2 1 0 11 4 1 0 7 5 1 0 M END > 103936 > Bioorg. Med. Chem. Lett. 13(10)-2003 1691-1694 > IMPDH > 3.2076 $$$$ SciTegic07090714152D 11 12 0 0 0 0 999 V2000 -4.6635 2.0821 0.0000 N 0 0 0.2917 0.7475 0.0000 C 0 0 1.7138 -1.2033 0.0000 N 0 0 -3.6202 1.4892 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 2.5889 0.0182 0.0000 C 0 0 1.7138 1.2033 0.0000 C 0 0 -1.0028 1.5132 0.0000 C 0 0 -2.3155 0.7475 0.0000 C 0 0 -1.0028 -1.5132 0.0000 C 0 0 -2.3155 -0.7475 0.0000 C 0 0 2 8 2 0 3 5 1 0 4 1 3 0 5 10 2 0 6 7 2 0 7 2 1 0 8 9 1 0 9 4 1 0 10 11 1 0 11 9 2 0 5 2 1 0 6 3 1 0 M END > 103934 > Bioorg. Med. Chem. Lett. 13(10)-2003 1691-1694 > IMPDH > 4.0044 $$$$ SciTegic07090714152D 12 13 0 0 0 0 999 V2000 0.0000 -0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 1.2964 1.4973 0.0000 N 0 0 1.2964 -1.4973 0.0000 C 0 0 -2.6111 0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 1.2964 -2.6973 0.0000 N 0 0 2.5929 0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -3.6486 1.3517 0.0000 Cl 0 0 2 1 1 0 3 2 2 0 4 1 2 0 5 2 1 0 6 1 1 0 7 8 2 0 8 4 1 0 9 6 1 0 10 11 1 0 11 6 2 0 12 7 1 0 10 5 2 0 3 7 1 0 M END > 103935 > Bioorg. Med. Chem. Lett. 13(10)-2003 1691-1694 > IMPDH > 3.7747 $$$$ SciTegic07090714152D 14 16 0 0 0 0 999 V2000 0.0000 -1.3190 0.0000 N 0 0 -1.2274 0.8244 0.0000 C 0 0 -1.2274 -0.6045 0.0000 C 0 0 1.2274 0.8244 0.0000 C 0 0 1.2274 -0.6045 0.0000 C 0 0 -2.4915 1.5389 0.0000 C 0 0 -2.4915 -1.3190 0.0000 C 0 0 -2.5030 2.7388 0.0000 O 0 0 2.4732 1.5389 0.0000 C 0 0 2.4732 -1.3190 0.0000 C 0 0 -3.7006 -0.6045 0.0000 C 0 0 -3.7006 0.8244 0.0000 C 0 0 3.7372 0.8244 0.0000 C 0 0 3.7372 -0.6045 0.0000 C 0 0 2 3 1 0 3 1 1 0 4 5 2 0 5 1 1 0 6 2 2 0 7 3 2 0 8 6 1 0 9 4 1 0 10 5 1 0 11 7 1 0 12 11 2 0 13 14 1 0 14 10 2 0 4 2 1 0 13 9 2 0 6 12 1 0 M END > 103932 > Bioorg. Med. Chem. Lett. 13(10)-2003 1691-1694 > IMPDH > 4.2676 $$$$ SciTegic07090714152D 18 20 0 0 0 0 999 V2000 0.0000 0.7486 0.0000 C 0 0 -2.6111 0.7486 0.0000 C 0 0 0.0000 -0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 -3.9086 1.5029 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 -5.5014 3.3065 0.0000 N 0 0 1.2964 1.4973 0.0000 C 0 0 1.2964 -1.4973 0.0000 N 0 0 2.5929 0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -6.2601 2.0125 0.0000 C 0 0 -5.2640 0.8910 0.0000 O 0 0 -4.0363 2.9847 0.0000 C 0 0 1.2964 2.6973 0.0000 O 0 0 -3.9091 -1.5019 0.0000 O 0 0 -3.9072 -2.7019 0.0000 C 0 0 2 4 1 0 3 1 1 0 4 1 2 0 5 2 2 0 6 2 1 0 7 3 2 0 8 15 1 0 9 1 1 0 10 3 1 0 11 9 1 0 12 11 2 0 13 14 1 0 14 6 1 0 15 6 2 0 16 9 2 0 17 5 1 0 18 17 1 0 5 7 1 0 12 10 1 0 8 13 2 0 M END > 100866 > Bioorg. Med. Chem. Lett. 13(3)-2003 543-546 > IMPDHII > 6.5229 $$$$ SciTegic07090714152D 19 20 0 0 0 0 999 V2000 -3.8933 3.7570 0.0000 N 0 0 1.2990 -0.7500 0.0000 C 0 0 -3.8912 5.2578 0.0000 C 0 0 -2.5951 3.0039 0.0000 C 0 0 2.5987 -1.5004 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 4.2010 -3.2956 0.0000 N 0 0 -3.8895 6.4578 0.0000 N 0 0 -1.2990 -0.7500 0.0000 C 0 0 -2.5973 1.5031 0.0000 N 0 0 1.2990 0.7500 0.0000 C 0 0 4.9531 -1.9978 0.0000 C 0 0 3.9511 -0.8815 0.0000 O 0 0 2.7343 -2.9815 0.0000 C 0 0 -1.2990 0.7500 0.0000 C 0 0 -1.5549 3.6021 0.0000 N 0 0 0.0000 1.5000 0.0000 C 0 0 -0.0031 -3.0008 0.0000 O 0 0 -1.0432 -3.5994 0.0000 C 0 0 2 11 1 0 3 1 1 0 4 1 2 0 5 2 1 0 6 9 1 0 7 14 1 0 8 3 3 0 9 15 2 0 10 4 1 0 11 17 2 0 12 13 1 0 13 5 1 0 14 5 2 0 15 10 1 0 16 4 1 0 17 15 1 0 18 6 1 0 19 18 1 0 2 6 2 0 7 12 2 0 M END > 63272 > Bioorg. Med. Chem. Lett. 12(20)-2002 2931-2934 > IMPDHII > 6.4815 $$$$ SciTegic07090714152D 20 22 0 0 0 0 999 V2000 -5.2109 0.7445 0.0000 C 0 0 -3.9122 1.4966 0.0000 N 0 0 -6.5121 1.4924 0.0000 N 0 0 -5.2090 -0.4555 0.0000 O 0 0 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 C 0 0 2.5929 -0.7486 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 -7.8109 0.7403 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 -9.1125 1.4859 0.0000 C 0 0 -7.8060 -0.7598 0.0000 C 0 0 -9.1025 -1.5141 0.0000 C 0 0 -10.4091 0.7316 0.0000 C 0 0 -10.4041 -0.7684 0.0000 C 0 0 2 1 1 0 3 1 1 0 4 1 2 0 5 2 1 0 6 7 1 0 7 5 2 0 8 13 2 0 9 10 1 0 10 11 2 0 11 5 1 0 12 3 1 0 13 9 1 0 14 15 2 0 15 6 1 0 16 12 2 0 17 12 1 0 18 17 2 0 19 16 1 0 20 18 1 0 20 19 2 0 6 9 2 0 14 8 1 0 M END > 103170 > Bioorg. Med. Chem. Lett. 13(7)-2003 1345-1348 > IMPDHII > 6.1308 $$$$ SciTegic07090714152D 21 23 0 0 0 0 999 V2000 1.7138 1.2033 0.0000 C 0 0 0.2917 0.7475 0.0000 C 0 0 2.5889 0.0182 0.0000 C 0 0 1.7138 -1.2033 0.0000 N 0 0 2.1812 2.6271 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 -1.0028 1.5132 0.0000 C 0 0 4.1182 4.3614 0.0000 S 0 0 3.6500 2.9355 0.0000 C 0 0 8.5244 5.2803 0.0000 N 0 0 1.3808 3.5211 0.0000 O 0 0 -1.0028 -1.5132 0.0000 C 0 0 5.5870 4.6698 0.0000 C 0 0 -2.3155 0.7475 0.0000 C 0 0 -2.3155 -0.7475 0.0000 C 0 0 6.0571 6.0943 0.0000 C 0 0 6.5858 3.5506 0.0000 C 0 0 -3.6217 1.4865 0.0000 O 0 0 7.5257 6.3996 0.0000 C 0 0 8.0544 3.8558 0.0000 C 0 0 -4.6560 0.8780 0.0000 C 0 0 2 1 1 0 3 1 2 0 4 3 1 0 5 1 1 0 6 2 2 0 7 2 1 0 8 9 1 0 9 5 1 0 10 20 1 0 11 5 2 0 12 6 1 0 13 8 1 0 14 7 2 0 15 14 1 0 16 13 2 0 17 13 1 0 18 14 1 0 19 16 1 0 20 17 2 0 21 18 1 0 4 6 1 0 12 15 2 0 10 19 2 0 M END > 103930 > Bioorg. Med. Chem. Lett. 13(10)-2003 1691-1694 > IMPDH > 4.4949 $$$$ SciTegic07090714152D 21 23 0 0 0 0 999 V2000 -2.5951 3.0039 0.0000 C 0 0 1.2990 -0.7500 0.0000 C 0 0 -3.8933 3.7570 0.0000 C 0 0 2.5987 -1.5004 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 4.2010 -3.2956 0.0000 N 0 0 -2.5973 1.5031 0.0000 N 0 0 -1.2990 -0.7500 0.0000 C 0 0 1.2990 0.7500 0.0000 C 0 0 4.9531 -1.9978 0.0000 C 0 0 3.9511 -0.8815 0.0000 O 0 0 -4.0312 5.2378 0.0000 O 0 0 2.7343 -2.9815 0.0000 C 0 0 -1.2990 0.7500 0.0000 C 0 0 -5.2447 3.1359 0.0000 C 0 0 -1.5549 3.6021 0.0000 O 0 0 -5.4984 5.5497 0.0000 C 0 0 -6.2484 4.2507 0.0000 C 0 0 0.0000 1.5000 0.0000 C 0 0 -0.0031 -3.0008 0.0000 O 0 0 -1.0432 -3.5994 0.0000 C 0 0 2 9 1 0 3 1 1 0 4 2 1 0 5 8 1 0 6 13 1 0 7 1 1 0 8 14 2 0 9 19 2 0 10 11 1 0 11 4 1 0 12 3 1 0 13 4 2 0 14 7 1 0 15 3 2 0 16 1 2 0 17 12 1 0 18 15 1 0 19 14 1 0 20 5 1 0 21 20 1 0 17 18 2 0 2 5 2 0 6 10 2 0 M END > 63147 > Bioorg. Med. Chem. Lett. 12(20)-2002 2879-2882 > IMPDHII > 5.6021 $$$$ SciTegic07090714152D 21 23 0 0 0 0 999 V2000 -5.2109 0.7445 0.0000 C 0 0 -3.9122 1.4966 0.0000 N 0 0 -6.5121 1.4924 0.0000 N 0 0 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -5.2090 -0.4555 0.0000 O 0 0 -1.2964 1.4973 0.0000 C 0 0 2.5929 -0.7486 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 -7.8109 0.7403 0.0000 C 0 0 -9.1121 1.4882 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 -10.4113 0.7384 0.0000 C 0 0 -9.1120 2.9883 0.0000 C 0 0 -10.4110 3.7384 0.0000 C 0 0 -11.7103 1.4885 0.0000 C 0 0 -11.7101 2.9885 0.0000 C 0 0 2 1 1 0 3 1 1 0 4 2 1 0 5 7 1 0 6 1 2 0 7 4 2 0 8 14 2 0 9 10 1 0 10 11 2 0 11 4 1 0 12 3 1 0 13 12 1 0 14 9 1 0 15 16 2 0 16 5 1 0 17 13 1 0 18 13 2 0 19 18 1 0 20 17 2 0 21 19 2 0 5 9 2 0 20 21 1 0 15 8 1 0 M END > 103174 > Bioorg. Med. Chem. Lett. 13(7)-2003 1345-1348 > IMPDHII > 6.3979 $$$$ SciTegic07090714152D 21 24 0 0 0 0 999 V2000 1.2274 0.8244 0.0000 C 0 0 -1.2274 0.8244 0.0000 C 0 0 1.2274 -0.6045 0.0000 C 0 0 -1.2274 -0.6045 0.0000 C 0 0 0.0000 -1.3190 0.0000 N 0 0 -3.7006 0.8244 0.0000 C 0 0 -2.4915 1.5389 0.0000 C 0 0 -2.4915 -1.3190 0.0000 C 0 0 -3.7006 -0.6045 0.0000 C 0 0 -5.0040 1.5682 0.0000 C 0 0 -6.6219 3.3496 0.0000 N 0 0 2.4732 1.5389 0.0000 C 0 0 -7.3628 2.0453 0.0000 C 0 0 -6.3513 0.9377 0.0000 O 0 0 -5.1525 3.0480 0.0000 C 0 0 2.4732 -1.3190 0.0000 C 0 0 3.7372 0.8244 0.0000 C 0 0 4.7737 1.4291 0.0000 O 0 0 3.7372 -0.6045 0.0000 C 0 0 -4.9998 -1.3577 0.0000 O 0 0 -4.9984 -2.5577 0.0000 C 0 0 2 1 1 0 3 1 2 0 4 2 1 0 5 3 1 0 6 7 1 0 7 2 2 0 8 4 2 0 9 6 2 0 10 6 1 0 11 15 1 0 12 1 1 0 13 14 1 0 14 10 1 0 15 10 2 0 16 3 1 0 17 12 1 0 18 17 2 0 19 17 1 0 20 9 1 0 21 20 1 0 5 4 1 0 19 16 1 0 9 8 1 0 11 13 2 0 M END > 102831 > Bioorg. Med. Chem. Lett. 13(7)-2003 1273-1276 > IMPDHII > 6.5376 $$$$ SciTegic07090714152D 22 24 0 0 0 0 999 V2000 -2.5951 3.0039 0.0000 C 0 0 4.2010 -3.2956 0.0000 N 0 0 2.5987 -1.5004 0.0000 C 0 0 -3.8933 3.7570 0.0000 N 0 0 -2.5973 1.5031 0.0000 N 0 0 4.9531 -1.9978 0.0000 C 0 0 3.9511 -0.8815 0.0000 O 0 0 2.7343 -2.9815 0.0000 C 0 0 1.2990 -0.7500 0.0000 C 0 0 -1.5549 3.6021 0.0000 O 0 0 -3.8912 5.2578 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 1.2990 0.7500 0.0000 C 0 0 -1.2990 0.7500 0.0000 C 0 0 -5.1876 6.0124 0.0000 C 0 0 -1.2990 -0.7500 0.0000 C 0 0 0.0000 1.5000 0.0000 C 0 0 -5.1824 7.5124 0.0000 C 0 0 -2.5844 7.5034 0.0000 C 0 0 -2.5896 6.0034 0.0000 C 0 0 -3.8808 8.2579 0.0000 C 0 0 -6.2196 8.1160 0.0000 C 0 0 2 8 1 0 3 9 1 0 4 1 1 0 5 1 1 0 6 7 1 0 7 3 1 0 8 3 2 0 9 13 2 0 10 1 2 0 11 4 1 0 12 16 2 0 13 17 1 0 14 5 1 0 15 11 1 0 16 14 1 0 17 14 2 0 18 15 2 0 19 20 1 0 20 11 2 0 21 19 2 0 22 18 1 0 9 12 1 0 21 18 1 0 2 6 2 0 M END > 104790 > Bioorg. Med. Chem. Lett. 13(12)-2003 2059-2063 > IMPDHII > 6.1938 $$$$ SciTegic07090714152D 22 24 0 0 0 0 999 V2000 1.7138 -1.2033 0.0000 C 0 0 1.7138 1.2033 0.0000 N 0 0 0.2917 0.7475 0.0000 C 0 0 2.5889 0.0182 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 -3.6267 2.9927 0.0000 C 0 0 2.1825 -2.6263 0.0000 C 0 0 2.5579 -3.7661 0.0000 N 0 0 -1.0028 1.5132 0.0000 C 0 0 -3.6187 1.4919 0.0000 N 0 0 -1.0028 -1.5132 0.0000 C 0 0 -4.9300 3.7369 0.0000 N 0 0 -2.3155 0.7475 0.0000 C 0 0 -2.5905 3.5979 0.0000 O 0 0 -2.3155 -0.7475 0.0000 C 0 0 2.0825 2.3453 0.0000 C 0 0 -4.9380 5.2378 0.0000 C 0 0 -6.2396 5.9835 0.0000 C 0 0 -3.6415 5.9922 0.0000 C 0 0 -3.6465 7.4922 0.0000 C 0 0 -6.2445 7.4835 0.0000 C 0 0 -4.9480 8.2378 0.0000 C 0 0 2 4 1 0 3 5 2 0 4 1 2 0 5 1 1 0 6 10 1 0 7 1 1 0 8 7 3 0 9 3 1 0 10 13 1 0 11 5 1 0 12 6 1 0 13 15 1 0 14 6 2 0 15 11 2 0 16 2 1 0 17 12 1 0 18 17 2 0 19 17 1 0 20 19 2 0 21 18 1 0 22 20 1 0 3 2 1 0 13 9 2 0 22 21 2 0 M END > 120711 > Bioorg. Med. Chem. Lett. 13(20)-2003 3557-3560 > IMPDHII > 6.2007 $$$$ SciTegic07090714152D 22 24 0 0 0 0 999 V2000 1.2990 -0.7500 0.0000 C 0 0 -2.5951 3.0039 0.0000 C 0 0 2.5987 -1.5004 0.0000 C 0 0 1.2990 0.7500 0.0000 C 0 0 4.2010 -3.2956 0.0000 N 0 0 -2.5973 1.5031 0.0000 N 0 0 0.0000 1.5000 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 4.9531 -1.9978 0.0000 C 0 0 3.9511 -0.8815 0.0000 O 0 0 2.7343 -2.9815 0.0000 C 0 0 -1.2990 0.7500 0.0000 C 0 0 -1.5549 3.6021 0.0000 O 0 0 -3.8933 3.7570 0.0000 C 0 0 -1.2990 -0.7500 0.0000 C 0 0 2.5972 1.5031 0.0000 O 0 0 -3.8934 5.2570 0.0000 C 0 0 -5.1925 3.0070 0.0000 C 0 0 2.5955 2.7031 0.0000 C 0 0 -5.1924 6.0070 0.0000 C 0 0 -6.4915 3.7571 0.0000 C 0 0 -6.4915 5.2571 0.0000 C 0 0 2 6 1 0 3 1 1 0 4 1 2 0 5 11 1 0 6 12 1 0 7 4 1 0 8 1 1 0 9 10 1 0 10 3 1 0 11 3 2 0 12 15 1 0 13 2 2 0 14 2 1 0 15 8 2 0 16 4 1 0 17 14 1 0 18 14 2 0 19 16 1 0 20 17 2 0 21 18 1 0 22 21 2 0 7 12 2 0 5 9 2 0 22 20 1 0 M END > 63135 > Bioorg. Med. Chem. Lett. 12(20)-2002 2879-2882 > IMPDHII > 6.2007 $$$$ SciTegic07090714152D 22 25 0 0 0 0 999 V2000 1.7138 -1.2033 0.0000 N 0 0 2.5889 0.0182 0.0000 C 0 0 -2.3155 0.7475 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 1.7138 1.2033 0.0000 C 0 0 0.2917 0.7475 0.0000 C 0 0 -1.0028 1.5132 0.0000 C 0 0 -2.3155 -0.7475 0.0000 C 0 0 -3.6168 1.4950 0.0000 C 0 0 -1.0028 -1.5132 0.0000 C 0 0 -5.9730 1.9836 0.0000 N 0 0 -5.2259 3.2843 0.0000 C 0 0 -3.7580 2.9756 0.0000 O 0 0 -4.9669 0.8711 0.0000 C 0 0 4.0896 0.0290 0.0000 C 0 0 -3.6187 -1.4919 0.0000 O 0 0 4.9234 1.2700 0.0000 C 0 0 4.7453 -1.3220 0.0000 C 0 0 -3.6251 -2.6919 0.0000 C 0 0 6.4199 1.1671 0.0000 C 0 0 6.2418 -1.4248 0.0000 C 0 0 7.0791 -0.1803 0.0000 C 0 0 2 1 1 0 3 8 2 0 4 1 1 0 5 2 2 0 6 4 1 0 7 6 2 0 8 10 1 0 9 3 1 0 10 4 2 0 11 14 1 0 12 13 1 0 13 9 1 0 14 9 2 0 15 2 1 0 16 8 1 0 17 15 1 0 18 15 2 0 19 16 1 0 20 17 2 0 21 18 1 0 22 21 2 0 6 5 1 0 3 7 1 0 20 22 1 0 11 12 2 0 M END > 102826 > Bioorg. Med. Chem. Lett. 13(7)-2003 1273-1276 > IMPDHII > 6.3010 $$$$ SciTegic07090714152D 22 25 0 0 0 0 999 V2000 1.2502 2.9107 0.0000 C 0 0 -0.2344 2.9107 0.0000 C 0 0 -0.7033 1.4651 0.0000 C 0 0 0.5079 0.6251 0.0000 N 0 0 1.6995 1.5237 0.0000 C 0 0 -2.7153 3.6921 0.0000 C 0 0 -1.2502 4.0242 0.0000 C 0 0 -2.1879 1.1135 0.0000 C 0 0 -3.2037 2.2270 0.0000 C 0 0 -3.7228 4.8044 0.0000 C 0 0 -4.7158 6.9965 0.0000 N 0 0 2.0902 4.1804 0.0000 C 0 0 -5.8214 5.9828 0.0000 C 0 0 -5.1989 4.6180 0.0000 O 0 0 -3.4100 6.2583 0.0000 C 0 0 3.5944 4.2781 0.0000 C 0 0 4.0431 5.3911 0.0000 O 0 0 -4.6688 1.9033 0.0000 O 0 0 3.0865 0.9767 0.0000 C 0 0 4.3953 1.7386 0.0000 C 0 0 4.6102 3.1646 0.0000 C 0 0 -5.0310 0.7593 0.0000 C 0 0 2 1 1 0 3 2 1 0 4 5 1 0 5 1 2 0 6 7 1 0 7 2 2 0 8 3 2 0 9 6 2 0 10 6 1 0 11 15 1 0 12 1 1 0 13 14 1 0 14 10 1 0 15 10 2 0 16 12 1 0 17 16 2 0 18 9 1 0 19 5 1 0 20 19 1 0 21 16 1 0 22 18 1 0 4 3 1 0 20 21 1 0 9 8 1 0 11 13 2 0 M END > 102830 > Bioorg. Med. Chem. Lett. 13(7)-2003 1273-1276 > IMPDHII > 6.8239 $$$$ SciTegic07090714152D 22 25 0 0 0 0 999 V2000 -5.2109 0.7445 0.0000 C 0 0 -6.5644 1.3610 0.0000 N 0 0 -5.3439 -0.7368 0.0000 O 0 0 -6.8101 -1.0536 0.0000 C 0 0 -7.5644 0.2430 0.0000 C 0 0 -3.9122 1.4966 0.0000 N 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 C 0 0 1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 N 0 0 -7.4160 -2.4266 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 -8.8861 -2.6983 0.0000 C 0 0 -6.4370 -3.5653 0.0000 C 0 0 -6.9376 -4.9793 0.0000 C 0 0 -9.3867 -4.1123 0.0000 C 0 0 -8.4125 -5.2528 0.0000 C 0 0 2 1 2 0 3 1 1 0 4 3 1 0 5 2 1 0 6 1 1 0 7 8 1 0 8 11 2 0 9 7 1 0 10 15 1 0 11 6 1 0 12 17 2 0 13 4 1 0 14 9 2 0 15 16 2 0 16 11 1 0 17 10 1 0 18 13 2 0 19 13 1 0 20 19 2 0 21 18 1 0 22 20 1 0 5 4 2 0 7 10 2 0 14 12 1 0 22 21 2 0 M END > 103180 > Bioorg. Med. Chem. Lett. 13(7)-2003 1345-1348 > IMPDHII > 7.2218 $$$$ SciTegic07090714152D 23 25 0 0 1 0 999 V2000 1.7138 1.2033 0.0000 N 0 0 2.1749 2.6315 0.0000 C 0 0 1 0 0 0 0.2917 0.7475 0.0000 C 0 0 3.5533 3.1779 0.0000 C 0 0 1 0 0 0 -1.0028 1.5132 0.0000 N 0 0 1.1949 3.7514 0.0000 O 0 0 2.5889 0.0182 0.0000 C 0 0 1.7138 -1.2033 0.0000 N 0 0 0.2917 -0.7475 0.0000 C 0 0 1.9824 5.0281 0.0000 C 0 0 1 0 0 0 3.4400 4.6736 0.0000 C 0 0 1 0 0 0 -0.6506 7.9979 0.0000 P 0 0 -2.3155 0.7475 0.0000 C 0 0 -2.3155 -0.7475 0.0000 N 0 0 1.4103 6.4127 0.0000 C 0 0 -0.0774 6.6109 0.0000 O 0 0 -1.0028 -1.5132 0.0000 C 0 0 -1.8401 8.1563 0.0000 O 0 0 4.5707 2.5416 0.0000 O 0 0 0.0810 8.9491 0.0000 O 0 0 -1.1083 9.1072 0.0000 O 0 0 -3.3560 1.3452 0.0000 Cl 0 0 4.3547 5.4503 0.0000 O 0 0 2 1 1 6 3 1 1 0 4 2 1 0 5 3 1 0 6 2 1 0 7 1 1 0 8 7 2 0 9 3 2 0 10 6 1 0 11 4 1 0 12 16 1 0 13 5 2 0 14 17 2 0 10 15 1 6 16 15 1 0 17 9 1 0 18 12 2 0 4 19 1 1 20 12 1 0 21 12 1 0 22 13 1 0 11 23 1 1 9 8 1 0 11 10 1 0 14 13 1 0 M END > 101134 > Bioorg. Med. Chem. Lett. 13(4)-2003 645-647 > IMPDH > 4.2076 $$$$ SciTegic07090714152D 23 26 0 0 0 0 999 V2000 -2.3155 0.7475 0.0000 C 0 0 1.7138 -1.2033 0.0000 N 0 0 2.5889 0.0182 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 0.2917 0.7475 0.0000 C 0 0 -1.0028 1.5132 0.0000 C 0 0 -2.3155 -0.7475 0.0000 C 0 0 1.7138 1.2033 0.0000 C 0 0 -3.6168 1.4950 0.0000 C 0 0 -1.0028 -1.5132 0.0000 C 0 0 -5.2262 3.2840 0.0000 N 0 0 -5.9732 1.9832 0.0000 C 0 0 -4.9669 0.8708 0.0000 O 0 0 -3.7582 2.9755 0.0000 C 0 0 4.0872 0.0320 0.0000 C 0 0 -3.6187 -1.4919 0.0000 O 0 0 4.8506 -1.2602 0.0000 C 0 0 -3.6251 -2.6919 0.0000 C 0 0 6.3505 -1.2485 0.0000 C 0 0 4.1108 -2.5652 0.0000 C 0 0 4.8709 -3.8583 0.0000 C 0 0 7.1107 -2.5417 0.0000 C 0 0 6.3709 -3.8465 0.0000 C 0 0 2 4 1 0 3 8 2 0 4 10 2 0 5 6 2 0 6 1 1 0 7 1 2 0 8 5 1 0 9 1 1 0 10 7 1 0 11 14 1 0 12 13 1 0 13 9 1 0 14 9 2 0 15 3 1 0 16 7 1 0 17 15 1 0 18 16 1 0 19 17 2 0 20 17 1 0 21 20 2 0 22 19 1 0 23 21 1 0 4 5 1 0 11 12 2 0 3 2 1 0 22 23 2 0 M END > 102832 > Bioorg. Med. Chem. Lett. 13(7)-2003 1273-1276 > IMPDHII > 6.2218 $$$$ SciTegic07090714152D 23 25 0 0 0 0 999 V2000 1.2990 -0.7500 0.0000 C 0 0 2.5987 -1.5004 0.0000 C 0 0 1.2990 0.7500 0.0000 C 0 0 4.2010 -3.2956 0.0000 N 0 0 -5.1894 6.0109 0.0000 C 0 0 -2.5951 3.0039 0.0000 C 0 0 0.0000 1.5000 0.0000 C 0 0 -5.3273 7.4917 0.0000 S 0 0 -3.8933 3.7570 0.0000 C 0 0 -3.8912 5.2578 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 4.9531 -1.9978 0.0000 C 0 0 3.9511 -0.8815 0.0000 O 0 0 2.7343 -2.9815 0.0000 C 0 0 -2.5973 1.5031 0.0000 N 0 0 -1.2990 0.7500 0.0000 C 0 0 -6.7945 7.8036 0.0000 C 0 0 -6.5408 5.3898 0.0000 C 0 0 -7.5445 6.5046 0.0000 C 0 0 -1.5549 3.6021 0.0000 O 0 0 -1.2990 -0.7500 0.0000 C 0 0 2.5972 1.5031 0.0000 O 0 0 2.5955 2.7031 0.0000 C 0 0 2 1 1 0 3 1 2 0 4 14 1 0 5 10 1 0 6 15 1 0 7 3 1 0 8 5 1 0 9 6 1 0 10 9 2 0 11 1 1 0 12 13 1 0 13 2 1 0 14 2 2 0 15 16 1 0 16 21 1 0 17 8 1 0 18 5 2 0 19 18 1 0 20 6 2 0 21 11 2 0 22 3 1 0 23 22 1 0 7 16 2 0 4 12 2 0 17 19 2 0 M END > 63168 > Bioorg. Med. Chem. Lett. 12(20)-2002 2879-2882 > IMPDHII > 7.1805 $$$$ SciTegic07090714152D 23 26 0 0 0 0 999 V2000 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 -3.9086 1.5029 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 5.4950 -3.2941 0.0000 N 0 0 -5.2640 0.8910 0.0000 S 0 0 6.2469 -1.9962 0.0000 C 0 0 5.2449 -0.8800 0.0000 O 0 0 4.0282 -2.9800 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 -4.0363 2.9847 0.0000 C 0 0 -6.2601 2.0125 0.0000 C 0 0 -5.5014 3.3065 0.0000 C 0 0 3.8911 1.5017 0.0000 O 0 0 3.8894 2.7017 0.0000 C 0 0 2 3 1 0 3 1 1 0 4 7 1 0 5 1 2 0 6 8 1 0 7 5 1 0 8 4 2 0 9 1 1 0 10 2 2 0 11 10 1 0 12 6 1 0 13 17 1 0 14 9 1 0 15 16 1 0 16 12 1 0 17 12 2 0 18 7 2 0 19 9 2 0 20 14 1 0 21 19 1 0 22 11 1 0 23 22 1 0 21 20 2 0 2 4 1 0 11 6 2 0 13 15 2 0 M END > 100861 > Bioorg. Med. Chem. Lett. 13(3)-2003 543-546 > IMPDHII > 7.2007 $$$$ SciTegic07090714152D 24 27 0 0 0 0 999 V2000 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 4.0328 -2.9796 0.0000 N 0 0 5.5005 -3.2891 0.0000 C 0 0 6.2485 -1.9889 0.0000 O 0 0 5.2430 -0.8758 0.0000 C 0 0 -3.9086 1.5029 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 3.8911 1.5017 0.0000 O 0 0 -5.2125 0.7617 0.0000 C 0 0 -3.8985 3.0029 0.0000 C 0 0 3.8894 2.7017 0.0000 C 0 0 -5.1925 3.7616 0.0000 C 0 0 -6.5065 1.5203 0.0000 C 0 0 -6.4965 3.0203 0.0000 C 0 0 2 1 1 0 3 1 1 0 4 2 1 0 5 7 1 0 6 11 2 0 7 3 1 0 8 3 2 0 9 6 1 0 10 1 2 0 11 10 1 0 12 9 1 0 13 12 2 0 14 15 1 0 15 9 2 0 16 4 1 0 17 7 2 0 18 11 1 0 19 16 2 0 20 16 1 0 21 18 1 0 22 20 2 0 23 19 1 0 24 22 1 0 6 8 1 0 5 4 2 0 14 13 1 0 24 23 2 0 M END > 104806 > Bioorg. Med. Chem. Lett. 13(12)-2003 2059-2063 > IMPDHII > 6.6778 $$$$ SciTegic07090714152D 24 26 0 0 0 0 999 V2000 1.2990 -0.7500 0.0000 C 0 0 2.5987 -1.5004 0.0000 C 0 0 1.2990 0.7500 0.0000 C 0 0 4.2010 -3.2956 0.0000 N 0 0 -2.5951 3.0039 0.0000 C 0 0 0.0000 1.5000 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 -3.8933 3.7570 0.0000 C 0 0 4.9531 -1.9978 0.0000 C 0 0 3.9511 -0.8815 0.0000 O 0 0 2.7343 -2.9815 0.0000 C 0 0 -2.5973 1.5031 0.0000 N 0 0 -3.8912 5.2578 0.0000 C 0 0 -1.2990 0.7500 0.0000 C 0 0 -6.4885 8.2609 0.0000 N 0 0 -1.5549 3.6021 0.0000 O 0 0 -1.2990 -0.7500 0.0000 C 0 0 2.5972 1.5031 0.0000 O 0 0 -5.1894 6.0109 0.0000 C 0 0 -5.1895 7.5109 0.0000 C 0 0 -7.7876 7.5110 0.0000 C 0 0 2.5955 2.7031 0.0000 C 0 0 -6.4886 5.2609 0.0000 C 0 0 -7.7876 6.0110 0.0000 C 0 0 2 1 1 0 3 1 2 0 4 11 1 0 5 12 1 0 6 3 1 0 7 1 1 0 8 5 1 0 9 10 1 0 10 2 1 0 11 2 2 0 12 14 1 0 13 8 2 0 14 17 1 0 15 20 1 0 16 5 2 0 17 7 2 0 18 3 1 0 19 13 1 0 20 19 2 0 21 24 1 0 22 18 1 0 23 19 1 0 24 23 2 0 6 14 2 0 4 9 2 0 21 15 2 0 M END > 63169 > Bioorg. Med. Chem. Lett. 12(20)-2002 2879-2882 > IMPDHII > 6.6778 $$$$ SciTegic07090714152D 24 26 0 0 0 0 999 V2000 0.2917 0.7475 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 -1.0028 1.5132 0.0000 C 0 0 -2.3155 0.7475 0.0000 C 0 0 -1.0028 -1.5132 0.0000 C 0 0 -2.3155 -0.7475 0.0000 C 0 0 1.7138 1.2033 0.0000 C 0 0 -3.6168 -1.4950 0.0000 C 0 0 2.5889 0.0182 0.0000 O 0 0 1.7138 -1.2033 0.0000 C 0 0 -3.6217 1.4865 0.0000 C 0 0 -4.2902 -2.7471 0.0000 C 0 0 -5.0376 -1.4466 0.0000 C 0 0 -4.9153 0.7255 0.0000 C 0 0 -10.1150 0.6811 0.0000 C 0 0 2.0825 2.3453 0.0000 O 0 0 -6.2216 1.4644 0.0000 C 0 0 -11.1595 1.2719 0.0000 O 0 0 -0.9991 2.7132 0.0000 O 0 0 -8.8215 1.4422 0.0000 C 0 0 -7.5151 0.7033 0.0000 C 0 0 -0.9991 -2.7132 0.0000 C 0 0 -10.1048 -0.5188 0.0000 O 0 0 -6.2318 2.6643 0.0000 C 0 0 2 1 2 0 3 1 1 0 4 3 2 0 5 2 1 0 6 4 1 0 7 1 1 0 8 6 1 0 9 7 1 0 10 2 1 0 11 4 1 0 12 8 1 0 13 8 1 0 14 11 1 0 15 20 1 0 16 7 2 0 17 14 2 0 18 15 2 0 19 3 1 0 20 21 1 0 21 17 1 0 22 5 1 0 23 15 1 0 24 17 1 0 9 10 1 0 5 6 2 0 13 12 1 0 M END > 33629 > J. Med. Chem. 39(21)-1996 4181-4196 > IMPDHII > 7.2950 $$$$ SciTegic07090714152D 24 27 0 0 0 0 999 V2000 1.7138 -1.2033 0.0000 C 0 0 2.5889 0.0182 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 1.7138 1.2033 0.0000 N 0 0 0.2917 0.7475 0.0000 C 0 0 -3.6267 2.9927 0.0000 C 0 0 2.1852 -2.6281 0.0000 C 0 0 3.7662 -4.4393 0.0000 N 0 0 -1.0028 1.5132 0.0000 C 0 0 -3.6187 1.4919 0.0000 N 0 0 -1.0028 -1.5132 0.0000 C 0 0 -4.9300 3.7369 0.0000 N 0 0 1.4028 -3.8873 0.0000 O 0 0 2.3840 -5.0218 0.0000 C 0 0 3.6393 -2.9446 0.0000 C 0 0 -2.3155 0.7475 0.0000 C 0 0 -2.5905 3.5979 0.0000 O 0 0 -2.3155 -0.7475 0.0000 C 0 0 -4.9380 5.2378 0.0000 C 0 0 -6.2396 5.9835 0.0000 C 0 0 -3.6415 5.9922 0.0000 C 0 0 -3.6465 7.4922 0.0000 C 0 0 -6.2445 7.4835 0.0000 C 0 0 -4.9480 8.2378 0.0000 C 0 0 2 1 2 0 3 1 1 0 4 2 1 0 5 3 2 0 6 10 1 0 7 1 1 0 8 15 1 0 9 5 1 0 10 16 1 0 11 3 1 0 12 6 1 0 13 7 1 0 14 13 1 0 15 7 2 0 16 18 1 0 17 6 2 0 18 11 2 0 19 12 1 0 20 19 1 0 21 19 2 0 22 21 1 0 23 20 2 0 24 22 2 0 5 4 1 0 8 14 2 0 16 9 2 0 24 23 1 0 M END > 63564 > Bioorg. Med. Chem. Lett. 12(22)-2002 3305-3308 > IMPDHII > 7.3979 $$$$ SciTegic07090714152D 25 28 0 0 0 0 999 V2000 -3.8056 3.8679 0.0000 S 0 0 -3.3372 5.2929 0.0000 C 0 0 -1.8372 5.2877 0.0000 N 0 0 -2.5951 3.0039 0.0000 C 0 0 1.2990 -0.7500 0.0000 C 0 0 2.5987 -1.5004 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 -1.3786 3.8595 0.0000 C 0 0 4.2010 -3.2956 0.0000 N 0 0 -1.2990 -0.7500 0.0000 C 0 0 -2.5973 1.5031 0.0000 N 0 0 1.2990 0.7500 0.0000 C 0 0 4.9531 -1.9978 0.0000 C 0 0 3.9511 -0.8815 0.0000 O 0 0 2.7343 -2.9815 0.0000 C 0 0 -1.2990 0.7500 0.0000 C 0 0 -4.2151 6.5101 0.0000 C 0 0 0.0000 1.5000 0.0000 C 0 0 -0.0031 -3.0008 0.0000 O 0 0 -5.7096 6.4704 0.0000 C 0 0 -3.4940 7.8274 0.0000 C 0 0 -1.0432 -3.5994 0.0000 C 0 0 -4.2774 9.1065 0.0000 C 0 0 -6.4930 7.7496 0.0000 C 0 0 -5.7769 9.0676 0.0000 C 0 0 2 1 1 0 3 2 2 0 4 1 1 0 5 12 1 0 6 5 1 0 7 10 1 0 8 4 2 0 9 15 1 0 10 16 2 0 11 4 1 0 12 18 2 0 13 14 1 0 14 6 1 0 15 6 2 0 16 11 1 0 17 2 1 0 18 16 1 0 19 7 1 0 20 17 2 0 21 17 1 0 22 19 1 0 23 21 2 0 24 20 1 0 25 23 1 0 8 3 1 0 7 5 2 0 25 24 2 0 9 13 2 0 M END > 82434 > Bioorg. Med. Chem. Lett. 12(21)-2002 3125-3128 > IMPDHII > 6.1192 $$$$ SciTegic07090714152D 25 28 0 0 0 0 999 V2000 -8.8299 2.9467 0.0000 C 0 0 -3.6217 1.4865 0.0000 C 0 0 -10.1347 3.6882 0.0000 C 0 0 -7.5360 3.7055 0.0000 C 0 0 -12.4938 4.1621 0.0000 N 0 0 -4.9153 0.7255 0.0000 N 0 0 -2.3155 0.7475 0.0000 C 0 0 0.2917 0.7475 0.0000 C 0 0 -6.2319 2.9644 0.0000 C 0 0 1.7138 -1.2033 0.0000 N 0 0 -1.0028 1.5132 0.0000 C 0 0 -8.8197 1.4467 0.0000 C 0 0 -11.7548 5.4674 0.0000 C 0 0 -10.2850 5.1678 0.0000 O 0 0 0.2917 -0.7475 0.0000 C 0 0 2.5889 0.0182 0.0000 C 0 0 -11.4808 3.0558 0.0000 C 0 0 -6.2216 1.4644 0.0000 C 0 0 1.7138 1.2033 0.0000 C 0 0 -3.6319 2.6865 0.0000 O 0 0 -2.3155 -0.7475 0.0000 C 0 0 -1.0028 -1.5132 0.0000 C 0 0 -7.5156 0.7056 0.0000 C 0 0 -7.5431 5.2063 0.0000 O 0 0 -6.5071 5.8119 0.0000 C 0 0 2 6 1 0 3 1 1 0 4 1 2 0 5 17 1 0 6 18 1 0 7 2 1 0 8 11 2 0 9 4 1 0 10 15 1 0 11 7 1 0 12 1 1 0 13 14 1 0 14 3 1 0 15 22 2 0 16 19 2 0 17 3 2 0 18 23 1 0 19 8 1 0 20 2 2 0 21 7 2 0 22 21 1 0 23 12 2 0 24 4 1 0 25 24 1 0 9 18 2 0 5 13 2 0 8 15 1 0 10 16 1 0 M END > 63139 > Bioorg. Med. Chem. Lett. 12(20)-2002 2879-2882 > IMPDHII > 6.2007 $$$$ SciTegic07090714152D 25 28 0 0 0 0 999 V2000 2.5889 0.0182 0.0000 C 0 0 1.7138 1.2033 0.0000 O 0 0 4.0872 0.0320 0.0000 C 0 0 1.7138 -1.2033 0.0000 C 0 0 9.3512 -1.2122 0.0000 C 0 0 10.8519 -1.1951 0.0000 C 0 0 8.6160 -2.5196 0.0000 C 0 0 13.1455 -1.9228 0.0000 N 0 0 4.8506 -1.2602 0.0000 N 0 0 0.2917 0.7475 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 7.1161 -2.5366 0.0000 C 0 0 8.5865 0.0783 0.0000 C 0 0 13.1309 -0.4229 0.0000 C 0 0 11.6998 0.0267 0.0000 O 0 0 11.7235 -2.4002 0.0000 C 0 0 6.3513 -1.2462 0.0000 C 0 0 4.6772 1.0770 0.0000 O 0 0 7.0866 0.0613 0.0000 C 0 0 9.3785 -3.8124 0.0000 O 0 0 -1.0028 1.5132 0.0000 C 0 0 -1.0028 -1.5132 0.0000 C 0 0 8.7888 -4.8575 0.0000 C 0 0 -2.3155 0.7475 0.0000 C 0 0 -2.3155 -0.7475 0.0000 C 0 0 2 1 1 0 3 1 1 0 4 1 2 0 5 13 1 0 6 5 1 0 7 12 1 0 8 16 1 0 9 3 1 0 10 2 1 0 11 4 1 0 12 17 2 0 13 19 2 0 14 15 1 0 15 6 1 0 16 6 2 0 17 9 1 0 18 3 2 0 19 17 1 0 20 7 1 0 21 10 2 0 22 11 2 0 23 20 1 0 24 21 1 0 25 22 1 0 11 10 1 0 25 24 2 0 5 7 2 0 8 14 2 0 M END > 63143 > Bioorg. Med. Chem. Lett. 12(20)-2002 2879-2882 > IMPDHII > 6.6778 $$$$ SciTegic07090714152D 25 28 0 0 0 0 999 V2000 0.0000 0.7486 0.0000 C 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 0.7486 0.0000 C 0 0 1.2964 -1.4973 0.0000 N 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 -3.9086 1.5029 0.0000 C 0 0 -5.5014 3.3065 0.0000 N 0 0 -6.2601 2.0125 0.0000 C 0 0 -5.2640 0.8910 0.0000 O 0 0 -4.0363 2.9847 0.0000 C 0 0 1.2964 2.6973 0.0000 O 0 0 3.8911 -1.5017 0.0000 C 0 0 -3.9091 -1.5019 0.0000 O 0 0 3.8890 -3.0026 0.0000 C 0 0 -3.9072 -2.7019 0.0000 C 0 0 5.1854 -3.7571 0.0000 C 0 0 2.5873 -3.7482 0.0000 C 0 0 2.5821 -5.2482 0.0000 C 0 0 5.1802 -5.2571 0.0000 C 0 0 3.8786 -6.0026 0.0000 C 0 0 2 1 1 0 3 8 1 0 4 2 1 0 5 1 1 0 6 7 2 0 7 5 1 0 8 1 2 0 9 2 2 0 10 3 2 0 11 3 1 0 12 15 1 0 13 14 1 0 14 11 1 0 15 11 2 0 16 5 2 0 17 6 1 0 18 10 1 0 19 17 1 0 20 18 1 0 21 19 2 0 22 19 1 0 23 22 2 0 24 21 1 0 25 23 1 0 9 10 1 0 6 4 1 0 12 13 2 0 25 24 2 0 M END > 100869 > Bioorg. Med. Chem. Lett. 13(3)-2003 543-546 > IMPDHII > 6.7447 $$$$ SciTegic07090714152D 26 28 0 0 0 0 999 V2000 1.2990 -0.7500 0.0000 C 0 0 2.5987 -1.5004 0.0000 C 0 0 1.2990 0.7500 0.0000 C 0 0 -2.5951 3.0039 0.0000 C 0 0 -3.8912 5.2578 0.0000 C 0 0 4.2010 -3.2956 0.0000 N 0 0 -3.8933 3.7570 0.0000 C 0 0 0.0000 1.5000 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 4.9531 -1.9978 0.0000 C 0 0 3.9511 -0.8815 0.0000 O 0 0 -2.5973 1.5031 0.0000 N 0 0 2.7343 -2.9815 0.0000 C 0 0 -5.1894 6.0109 0.0000 N 0 0 -1.2990 0.7500 0.0000 C 0 0 -1.5549 3.6021 0.0000 O 0 0 -2.8509 5.8560 0.0000 O 0 0 -1.2990 -0.7500 0.0000 C 0 0 2.5972 1.5031 0.0000 O 0 0 -5.1873 7.5117 0.0000 C 0 0 2.5955 2.7031 0.0000 C 0 0 -6.4837 8.2663 0.0000 C 0 0 -3.8856 8.2573 0.0000 C 0 0 -3.8805 9.7573 0.0000 C 0 0 -6.4785 9.7663 0.0000 C 0 0 -5.1769 10.5118 0.0000 C 0 0 2 1 1 0 3 1 2 0 4 12 1 0 5 7 1 0 6 13 1 0 7 4 1 0 8 3 1 0 9 1 1 0 10 11 1 0 11 2 1 0 12 15 1 0 13 2 2 0 14 5 1 0 15 18 1 0 16 4 2 0 17 5 2 0 18 9 2 0 19 3 1 0 20 14 1 0 21 19 1 0 22 20 2 0 23 20 1 0 24 23 2 0 25 22 1 0 26 24 1 0 8 15 2 0 6 10 2 0 26 25 2 0 M END > 2679 > Bioorg. Med. Chem. Lett. 12(9)-2002 1323-1326 > IMPDHII > 6.3979 $$$$ SciTegic07090714152D 26 29 0 0 0 0 999 V2000 1.7138 -1.2033 0.0000 C 0 0 1.7138 1.2033 0.0000 N 0 0 0.2917 0.7475 0.0000 C 0 0 -3.6267 2.9927 0.0000 C 0 0 -2.8841 5.2815 0.0000 C 0 0 2.5889 0.0182 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 -4.8430 3.8486 0.0000 N 0 0 -2.4160 3.8564 0.0000 O 0 0 -4.3841 5.2767 0.0000 C 0 0 2.1825 -2.6263 0.0000 C 0 0 2.5579 -3.7661 0.0000 N 0 0 -2.0059 6.4985 0.0000 C 0 0 -1.0028 1.5132 0.0000 C 0 0 -3.6187 1.4919 0.0000 N 0 0 -1.0028 -1.5132 0.0000 C 0 0 -2.3155 0.7475 0.0000 C 0 0 -2.5149 7.9042 0.0000 C 0 0 -2.3155 -0.7475 0.0000 C 0 0 2.0825 2.3453 0.0000 C 0 0 -4.3998 9.2981 0.0000 N 0 0 -3.9921 8.1695 0.0000 C 0 0 -0.5285 6.2297 0.0000 C 0 0 -1.5481 9.0511 0.0000 C 0 0 0.4383 7.3766 0.0000 C 0 0 -0.0715 8.7873 0.0000 C 0 0 2 6 1 0 3 7 2 0 4 15 1 0 5 9 1 0 6 1 2 0 7 1 1 0 8 4 2 0 9 4 1 0 10 8 1 0 11 1 1 0 12 11 3 0 13 5 1 0 14 3 1 0 15 17 1 0 16 7 1 0 17 19 1 0 18 13 2 0 19 16 2 0 20 2 1 0 21 22 1 0 22 18 1 0 23 13 1 0 24 18 1 0 25 23 2 0 26 25 1 0 3 2 1 0 17 14 2 0 10 5 2 0 26 24 2 0 M END > 120721 > Bioorg. Med. Chem. Lett. 13(20)-2003 3557-3560 > IMPDHII > 6.5528 $$$$ SciTegic07090714152D 26 30 0 0 0 0 999 V2000 1.7138 -1.2033 0.0000 C 0 0 -3.6267 2.9927 0.0000 C 0 0 2.5889 0.0182 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 -4.8430 3.8486 0.0000 N 0 0 -2.4160 3.8564 0.0000 O 0 0 1.7138 1.2033 0.0000 N 0 0 -2.8841 5.2815 0.0000 C 0 0 0.2917 0.7475 0.0000 C 0 0 2.1852 -2.6281 0.0000 C 0 0 -4.3841 5.2767 0.0000 C 0 0 3.7662 -4.4393 0.0000 N 0 0 -3.6187 1.4919 0.0000 N 0 0 -1.0028 1.5132 0.0000 C 0 0 -1.0028 -1.5132 0.0000 C 0 0 1.4028 -3.8873 0.0000 O 0 0 2.3840 -5.0218 0.0000 C 0 0 3.6393 -2.9446 0.0000 C 0 0 -2.3155 0.7475 0.0000 C 0 0 -2.0059 6.4985 0.0000 C 0 0 -2.3155 -0.7475 0.0000 C 0 0 -2.5149 7.9042 0.0000 C 0 0 -0.5285 6.2297 0.0000 C 0 0 0.4383 7.3766 0.0000 C 0 0 -1.5481 9.0511 0.0000 C 0 0 -0.0715 8.7873 0.0000 C 0 0 2 13 1 0 3 1 2 0 4 1 1 0 5 2 2 0 6 2 1 0 7 3 1 0 8 6 1 0 9 4 2 0 10 1 1 0 11 5 1 0 12 18 1 0 13 19 1 0 14 9 1 0 15 4 1 0 16 10 1 0 17 16 1 0 18 10 2 0 19 21 1 0 20 8 1 0 21 15 2 0 22 20 2 0 23 20 1 0 24 23 2 0 25 22 1 0 26 24 1 0 9 7 1 0 12 17 2 0 19 14 2 0 8 11 2 0 26 25 2 0 M END > 63570 > Bioorg. Med. Chem. Lett. 12(22)-2002 3305-3308 > IMPDHII > 7.0315 $$$$ SciTegic07090714152D 27 30 0 0 0 0 999 V2000 6.9854 8.9480 0.0000 C 0 0 1.7138 -1.2033 0.0000 N 0 0 1.7138 1.2033 0.0000 C 0 0 7.4507 10.3748 0.0000 C 0 0 2.5889 0.0182 0.0000 C 0 0 5.5178 8.6377 0.0000 C 0 0 8.8757 12.3138 0.0000 N 0 0 2.1812 2.6271 0.0000 C 0 0 0.2917 0.7475 0.0000 C 0 0 4.1182 4.3614 0.0000 C 0 0 5.0528 7.2117 0.0000 C 0 0 3.6500 2.9355 0.0000 C 0 0 7.9879 7.8322 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 7.4504 12.7811 0.0000 C 0 0 6.5655 11.5700 0.0000 O 0 0 8.8717 10.8138 0.0000 C 0 0 5.5870 4.6698 0.0000 N 0 0 6.0553 6.0958 0.0000 C 0 0 3.3178 5.2555 0.0000 O 0 0 7.5228 6.4061 0.0000 C 0 0 4.5125 9.7521 0.0000 O 0 0 -1.0028 1.5132 0.0000 C 0 0 -1.0028 -1.5132 0.0000 C 0 0 3.3388 9.5022 0.0000 C 0 0 -2.3155 0.7475 0.0000 C 0 0 -2.3155 -0.7475 0.0000 C 0 0 2 5 1 0 3 8 1 0 4 1 1 0 5 3 2 0 6 1 2 0 7 17 1 0 8 12 2 0 9 3 1 0 10 18 1 0 11 6 1 0 12 10 1 0 13 1 1 0 14 9 2 0 15 16 1 0 16 4 1 0 17 4 2 0 18 19 1 0 19 21 1 0 20 10 2 0 21 13 2 0 22 6 1 0 23 9 1 0 24 14 1 0 25 22 1 0 26 23 2 0 27 26 1 0 11 19 2 0 7 15 2 0 2 14 1 0 27 24 2 0 M END > 63172 > Bioorg. Med. Chem. Lett. 12(20)-2002 2879-2882 > IMPDHII > 6.3872 $$$$ SciTegic07090714152D 27 30 0 0 0 0 999 V2000 1.2990 -0.7500 0.0000 N 0 0 1.2990 0.7500 0.0000 C 0 0 -1.2990 -0.7500 0.0000 N 0 0 0.0000 -1.5000 0.0000 C 0 0 0.0000 1.5000 0.0000 N 0 0 -1.2990 0.7500 0.0000 C 0 0 2.5847 6.0040 0.0000 C 0 0 0.0000 -3.0008 0.0000 C 0 0 2.5795 7.5047 0.0000 C 0 0 3.8863 5.2585 0.0000 C 0 0 3.3252 9.7926 0.0000 N 0 0 2.5972 1.5031 0.0000 N 0 0 3.8915 3.7585 0.0000 C 0 0 1.2883 5.2495 0.0000 C 0 0 1.8252 9.7898 0.0000 C 0 0 1.3644 8.3623 0.0000 O 0 0 -1.2122 -3.8625 0.0000 O 0 0 3.7914 8.3669 0.0000 C 0 0 2.5951 3.0039 0.0000 C 0 0 1.2149 -3.8587 0.0000 C 0 0 -0.7464 -5.2884 0.0000 C 0 0 0.7536 -5.2860 0.0000 C 0 0 -2.5973 1.5031 0.0000 N 0 0 1.2934 3.7495 0.0000 C 0 0 5.1850 6.0107 0.0000 O 0 0 -2.5956 2.7031 0.0000 C 0 0 6.2255 5.4129 0.0000 C 0 0 2 1 1 0 3 4 1 0 4 1 2 0 5 2 2 0 6 3 2 0 7 14 2 0 8 4 1 0 9 7 1 0 10 13 2 0 11 18 1 0 12 2 1 0 13 19 1 0 14 24 1 0 15 16 1 0 16 9 1 0 17 8 1 0 18 9 2 0 19 12 1 0 20 8 2 0 21 17 1 0 22 20 1 0 23 6 1 0 24 19 2 0 25 10 1 0 26 23 1 0 27 25 1 0 6 5 1 0 21 22 2 0 7 10 1 0 11 15 2 0 M END > 4776 > Bioorg. Med. Chem. Lett. 12(16)-2002 2137-2140 > IMPDHII > 7.2441 $$$$ SciTegic07090714152D 27 30 0 0 0 0 999 V2000 1.2990 -0.7500 0.0000 N 0 0 1.2990 0.7500 0.0000 C 0 0 -1.2990 -0.7500 0.0000 N 0 0 0.0000 -1.5000 0.0000 C 0 0 0.0000 1.5000 0.0000 N 0 0 -1.2990 0.7500 0.0000 C 0 0 2.5847 6.0040 0.0000 C 0 0 2.5795 7.5047 0.0000 C 0 0 3.8863 5.2585 0.0000 C 0 0 3.3252 9.7926 0.0000 N 0 0 2.5972 1.5031 0.0000 N 0 0 3.8915 3.7585 0.0000 C 0 0 1.2883 5.2495 0.0000 C 0 0 1.8252 9.7898 0.0000 C 0 0 1.3644 8.3623 0.0000 O 0 0 3.7914 8.3669 0.0000 C 0 0 2.5951 3.0039 0.0000 C 0 0 0.0000 -3.0008 0.0000 C 0 0 -2.3383 1.3500 0.0000 N 0 0 1.2934 3.7495 0.0000 C 0 0 5.1850 6.0107 0.0000 O 0 0 -1.2978 -3.7529 0.0000 C 0 0 1.3002 -3.7488 0.0000 C 0 0 6.2255 5.4129 0.0000 C 0 0 -1.2955 -5.2529 0.0000 C 0 0 1.3026 -5.2488 0.0000 C 0 0 0.0048 -6.0009 0.0000 C 0 0 2 1 1 0 3 4 1 0 4 1 2 0 5 2 2 0 6 3 2 0 7 13 2 0 8 7 1 0 9 12 2 0 10 16 1 0 11 2 1 0 12 17 1 0 13 20 1 0 14 15 1 0 15 8 1 0 16 8 2 0 17 11 1 0 18 4 1 0 19 6 1 0 20 17 2 0 21 9 1 0 22 18 1 0 23 18 2 0 24 21 1 0 25 22 2 0 26 23 1 0 27 26 2 0 5 6 1 0 25 27 1 0 7 9 1 0 10 14 2 0 M END > 4756 > Bioorg. Med. Chem. Lett. 12(16)-2002 2137-2140 > IMPDHII > 7.2676 $$$$ SciTegic07090714152D 27 31 0 0 0 0 999 V2000 2.5889 0.0182 0.0000 C 0 0 4.0896 0.0290 0.0000 C 0 0 1.7138 1.2033 0.0000 C 0 0 1.7138 -1.2033 0.0000 N 0 0 0.2917 0.7475 0.0000 C 0 0 0.2917 -0.7475 0.0000 C 0 0 -2.3155 0.7475 0.0000 C 0 0 4.8196 1.2981 0.0000 C 0 0 -1.0028 1.5132 0.0000 C 0 0 5.0388 -1.1021 0.0000 C 0 0 6.2850 0.9656 0.0000 S 0 0 -1.0028 -1.5132 0.0000 C 0 0 -2.3155 -0.7475 0.0000 C 0 0 -3.6168 1.4950 0.0000 C 0 0 -5.2262 3.2840 0.0000 N 0 0 6.4167 -0.5220 0.0000 C 0 0 -5.9732 1.9832 0.0000 C 0 0 -4.9669 0.8708 0.0000 O 0 0 -3.7582 2.9755 0.0000 C 0 0 2.1812 2.6271 0.0000 C 0 0 3.3556 2.8737 0.0000 O 0 0 -3.6187 -1.4919 0.0000 O 0 0 4.8354 -2.5922 0.0000 C 0 0 7.6248 -1.4179 0.0000 C 0 0 -3.6251 -2.6919 0.0000 C 0 0 6.0505 -3.5049 0.0000 C 0 0 7.4284 -2.9248 0.0000 C 0 0 2 1 1 0 3 1 2 0 4 1 1 0 5 3 1 0 6 4 1 0 7 9 1 0 8 2 2 0 9 5 2 0 10 2 1 0 11 8 1 0 12 6 2 0 13 12 1 0 14 7 1 0 15 19 1 0 16 10 2 0 17 18 1 0 18 14 1 0 19 14 2 0 20 3 1 0 21 20 2 0 22 13 1 0 23 10 1 0 24 16 1 0 25 22 1 0 26 23 2 0 27 26 1 0 6 5 1 0 16 11 1 0 13 7 2 0 24 27 2 0 15 17 2 0 M END > 102836 > Bioorg. Med. Chem. Lett. 13(7)-2003 1273-1276 > IMPDHII > 7.5229 $$$$ SciTegic07090714152D 28 31 0 0 0 0 999 V2000 -11.7101 2.9885 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 -13.0097 3.7390 0.0000 C 0 0 -10.4110 3.7384 0.0000 C 0 0 -15.3656 4.2292 0.0000 N 0 0 -6.5121 1.4924 0.0000 C 0 0 -9.1120 2.9883 0.0000 C 0 0 -11.7103 1.4885 0.0000 C 0 0 -5.2109 0.7445 0.0000 C 0 0 -14.6175 5.5294 0.0000 C 0 0 -13.1498 5.2197 0.0000 O 0 0 0.0000 0.7486 0.0000 C 0 0 -14.3602 3.1160 0.0000 C 0 0 -7.8109 0.7403 0.0000 N 0 0 -3.9122 1.4966 0.0000 C 0 0 -9.1121 1.4882 0.0000 C 0 0 -2.6111 0.7486 0.0000 C 0 0 -6.5141 2.6924 0.0000 O 0 0 0.0000 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 -10.4113 0.7384 0.0000 C 0 0 -10.4077 5.2392 0.0000 O 0 0 -2.6111 -0.7486 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 -9.3676 5.8376 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 2 17 2 0 3 1 1 0 4 1 2 0 5 13 1 0 6 14 1 0 7 4 1 0 8 1 1 0 9 6 1 0 10 11 1 0 11 3 1 0 12 2 1 0 13 3 2 0 14 16 1 0 15 9 2 0 16 21 1 0 17 15 1 0 18 6 2 0 19 20 1 0 20 23 2 0 21 8 2 0 22 4 1 0 23 17 1 0 24 12 2 0 25 19 2 0 26 22 1 0 27 24 1 0 28 25 1 0 7 16 2 0 5 10 2 0 12 19 1 0 28 27 2 0 M END > 63171 > Bioorg. Med. Chem. Lett. 12(20)-2002 2879-2882 > IMPDHII > 6.2007 $$$$ SciTegic07090714152D 28 32 0 0 0 0 999 V2000 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 -6.5147 1.5352 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 -5.2294 0.7541 0.0000 C 0 0 -3.9086 1.5029 0.0000 C 0 0 5.4950 -3.2941 0.0000 N 0 0 6.2469 -1.9962 0.0000 C 0 0 5.2449 -0.8800 0.0000 O 0 0 -6.4968 3.0302 0.0000 C 0 0 4.0282 -2.9800 0.0000 C 0 0 -7.9421 1.0965 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 -3.8898 2.9990 0.0000 C 0 0 -5.1933 3.7804 0.0000 C 0 0 -7.9134 3.5029 0.0000 C 0 0 -8.8030 2.2919 0.0000 C 0 0 3.8911 1.5017 0.0000 O 0 0 -8.3244 -0.0410 0.0000 O 0 0 3.8894 2.7017 0.0000 C 0 0 2 3 1 0 3 1 1 0 4 7 1 0 5 1 2 0 6 8 1 0 7 5 1 0 8 4 2 0 9 2 2 0 10 9 1 0 11 13 2 0 12 6 1 0 13 14 1 0 14 1 1 0 15 19 1 0 16 17 1 0 17 12 1 0 18 23 2 0 19 12 2 0 20 11 1 0 21 7 2 0 22 14 2 0 23 22 1 0 24 18 1 0 25 20 1 0 26 10 1 0 27 20 1 0 28 26 1 0 2 4 1 0 18 11 1 0 10 6 2 0 25 24 1 0 15 16 2 0 M END > 100905 > Bioorg. Med. Chem. Lett. 13(3)-2003 547-551 > IMPDHII > 7.5528 $$$$ SciTegic07090714152D 29 33 0 0 0 0 999 V2000 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 -6.5182 1.5178 0.0000 C 0 0 -5.2260 0.7619 0.0000 C 0 0 -3.9086 1.5029 0.0000 C 0 0 5.4950 -3.2941 0.0000 N 0 0 6.2469 -1.9962 0.0000 C 0 0 5.2449 -0.8800 0.0000 O 0 0 4.0282 -2.9800 0.0000 C 0 0 -6.5098 3.0151 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 -7.8188 0.7764 0.0000 C 0 0 -3.8988 3.0005 0.0000 C 0 0 -5.2093 3.7564 0.0000 C 0 0 3.8911 1.5017 0.0000 O 0 0 -7.8255 -0.4236 0.0000 O 0 0 -9.1027 3.0295 0.0000 C 0 0 -7.8021 3.7709 0.0000 C 0 0 -9.1110 1.5323 0.0000 C 0 0 3.8894 2.7017 0.0000 C 0 0 2 3 1 0 3 1 1 0 4 7 1 0 5 1 2 0 6 8 1 0 7 5 1 0 8 4 2 0 9 2 2 0 10 9 1 0 11 6 1 0 12 13 2 0 13 14 1 0 14 1 1 0 15 18 1 0 16 17 1 0 17 11 1 0 18 11 2 0 19 23 2 0 20 7 2 0 21 12 1 0 22 14 2 0 23 22 1 0 24 10 1 0 25 21 1 0 26 27 1 0 27 19 1 0 28 21 1 0 29 24 1 0 2 4 1 0 19 12 1 0 10 6 2 0 26 28 1 0 15 16 2 0 M END > 100900 > Bioorg. Med. Chem. Lett. 13(3)-2003 547-551 > IMPDHII > 7.0809 $$$$ SciTegic07090714152D 29 33 0 0 0 0 999 V2000 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 -7.8112 0.7787 0.0000 N 0 0 5.4950 -3.2941 0.0000 N 0 0 -3.9086 1.5029 0.0000 C 0 0 -6.5065 1.5203 0.0000 C 0 0 -5.2125 0.7617 0.0000 C 0 0 6.2469 -1.9962 0.0000 C 0 0 5.2449 -0.8800 0.0000 O 0 0 4.0282 -2.9800 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 3.8911 1.5017 0.0000 O 0 0 -7.9613 -0.7010 0.0000 C 0 0 -9.1574 1.4108 0.0000 C 0 0 -3.8985 3.0029 0.0000 C 0 0 -6.4965 3.0203 0.0000 C 0 0 -5.1925 3.7616 0.0000 C 0 0 3.8894 2.7017 0.0000 C 0 0 -10.1703 0.3044 0.0000 C 0 0 -9.4311 -1.0008 0.0000 C 0 0 2 3 1 0 3 1 1 0 4 7 1 0 5 1 2 0 6 8 1 0 7 5 1 0 8 4 2 0 9 2 2 0 10 9 1 0 11 6 1 0 12 15 1 0 13 19 1 0 14 1 1 0 15 16 2 0 16 14 1 0 17 18 1 0 18 11 1 0 19 11 2 0 20 7 2 0 21 10 1 0 22 12 1 0 23 12 1 0 24 14 2 0 25 26 2 0 26 24 1 0 27 21 1 0 28 23 1 0 29 22 1 0 2 4 1 0 25 15 1 0 10 6 2 0 29 28 1 0 13 17 2 0 M END > 100895 > Bioorg. Med. Chem. Lett. 13(3)-2003 547-551 > IMPDHII > 7.6021 $$$$ SciTegic07090714152D 30 32 0 0 0 0 999 V2000 2.5987 -1.5004 0.0000 C 0 0 3.9511 -0.8815 0.0000 C 0 0 1.2990 -0.7500 0.0000 C 0 0 -3.8933 3.7570 0.0000 C 0 0 -2.5951 3.0039 0.0000 C 0 0 4.9531 -1.9978 0.0000 N 0 0 1.2990 0.7500 0.0000 C 0 0 -2.5973 1.5031 0.0000 N 0 0 -3.8912 5.2578 0.0000 N 0 0 4.2010 -3.2956 0.0000 C 0 0 2.7343 -2.9815 0.0000 O 0 0 0.0000 1.5000 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 -1.2990 0.7500 0.0000 C 0 0 4.2568 0.5852 0.0000 C 0 0 -4.9336 3.1588 0.0000 O 0 0 -1.5549 3.6021 0.0000 O 0 0 -5.1894 6.0109 0.0000 C 0 0 -1.2990 -0.7500 0.0000 C 0 0 2.5972 1.5031 0.0000 O 0 0 5.6819 1.0556 0.0000 C 0 0 -5.1877 7.2109 0.0000 C 0 0 -6.2297 5.4127 0.0000 C 0 0 -6.2277 6.6125 0.0000 C 0 0 2.5955 2.7031 0.0000 C 0 0 5.9901 2.5237 0.0000 C 0 0 6.7994 0.0549 0.0000 C 0 0 8.2247 0.5221 0.0000 C 0 0 7.4154 2.9909 0.0000 C 0 0 8.5328 1.9902 0.0000 C 0 0 2 1 2 0 3 1 1 0 4 5 1 0 5 8 1 0 6 2 1 0 7 3 2 0 8 14 1 0 9 4 1 0 10 11 1 0 11 1 1 0 12 7 1 0 13 3 1 0 14 19 1 0 15 2 1 0 16 4 2 0 17 5 2 0 18 9 1 0 19 13 2 0 20 7 1 0 21 15 1 0 22 18 1 0 23 18 1 0 24 18 1 0 25 20 1 0 26 21 2 0 27 21 1 0 28 27 2 0 29 26 1 0 30 28 1 0 10 6 2 0 14 12 2 0 30 29 2 0 M END > 103927 > Bioorg. Med. Chem. Lett. 13(10)-2003 1691-1694 > IMPDH > 4.4559 $$$$ SciTegic07090714152D 30 34 0 0 0 0 999 V2000 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 -2.6111 0.7486 0.0000 C 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 6.2485 -1.9889 0.0000 N 0 0 -7.7912 3.7793 0.0000 N 0 0 -3.9086 1.5029 0.0000 C 0 0 5.5005 -3.2891 0.0000 C 0 0 4.0328 -2.9796 0.0000 O 0 0 -6.4965 3.0203 0.0000 C 0 0 5.2430 -0.8758 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 -5.2125 0.7617 0.0000 C 0 0 -3.8985 3.0029 0.0000 C 0 0 -5.1925 3.7616 0.0000 C 0 0 -6.5065 1.5203 0.0000 C 0 0 -10.3769 5.3008 0.0000 O 0 0 3.8911 1.5017 0.0000 O 0 0 -9.0965 3.0402 0.0000 C 0 0 -7.7789 5.2793 0.0000 C 0 0 -9.0717 6.0401 0.0000 C 0 0 -10.3893 3.8009 0.0000 C 0 0 3.8894 2.7017 0.0000 C 0 0 2 1 1 0 3 2 1 0 4 1 1 0 5 7 1 0 6 10 2 0 7 4 1 0 8 4 2 0 9 1 2 0 10 9 1 0 11 6 1 0 12 18 1 0 13 17 1 0 14 3 1 0 15 16 1 0 16 11 1 0 17 22 2 0 18 11 2 0 19 7 2 0 20 14 1 0 21 14 2 0 22 21 1 0 23 20 2 0 24 28 1 0 25 10 1 0 26 13 1 0 27 13 1 0 28 27 1 0 29 26 1 0 30 25 1 0 6 8 1 0 5 3 2 0 17 23 1 0 12 15 2 0 24 29 1 0 M END > 100889 > Bioorg. Med. Chem. Lett. 13(3)-2003 547-551 > IMPDHII > 7.6778 $$$$ SciTegic07090714152D 31 35 0 0 0 0 999 V2000 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 -7.8112 0.7787 0.0000 N 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 5.4950 -3.2941 0.0000 N 0 0 -3.9086 1.5029 0.0000 C 0 0 -6.5065 1.5203 0.0000 C 0 0 -10.4217 -0.6999 0.0000 N 0 0 -5.2125 0.7617 0.0000 C 0 0 6.2469 -1.9962 0.0000 C 0 0 5.2449 -0.8800 0.0000 O 0 0 4.0282 -2.9800 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 -7.8237 -0.7214 0.0000 C 0 0 -9.1041 1.5393 0.0000 C 0 0 -10.4093 0.8001 0.0000 C 0 0 -9.1289 -1.4606 0.0000 C 0 0 3.8911 1.5017 0.0000 O 0 0 -11.4659 -1.2913 0.0000 C 0 0 -3.8985 3.0029 0.0000 C 0 0 -6.4965 3.0203 0.0000 C 0 0 -5.1925 3.7616 0.0000 C 0 0 3.8894 2.7017 0.0000 C 0 0 2 3 1 0 3 1 1 0 4 7 1 0 5 1 2 0 6 8 1 0 7 5 1 0 8 4 2 0 9 15 1 0 10 2 2 0 11 10 1 0 12 6 1 0 13 20 1 0 14 1 1 0 15 17 2 0 16 24 1 0 17 14 1 0 18 19 1 0 19 12 1 0 20 12 2 0 21 7 2 0 22 9 1 0 23 9 1 0 24 23 1 0 25 22 1 0 26 11 1 0 27 16 1 0 28 14 2 0 29 30 2 0 30 28 1 0 31 26 1 0 2 4 1 0 29 15 1 0 11 6 2 0 16 25 1 0 13 18 2 0 M END > 100891 > Bioorg. Med. Chem. Lett. 13(3)-2003 547-551 > IMPDHII > 7.7959 $$$$ SciTegic07090714152D 31 32 0 0 1 0 999 V2000 -2.5951 3.0039 0.0000 C 0 0 -7.7663 10.5283 0.0000 C 0 0 3.6380 -2.1004 0.0000 N 0 0 -11.3788 15.6508 0.0000 N 0 0 1.2990 -0.7500 0.0000 C 0 0 2.5988 -1.5004 0.0000 C 0 0 0.0000 -1.5000 0.0000 C 0 0 -2.5973 1.5031 0.0000 N 0 0 -3.8933 3.7570 0.0000 N 0 0 -1.2990 -0.7500 0.0000 C 0 0 -10.3429 15.0451 0.0000 C 0 0 -6.4707 9.7708 0.0000 N 0 0 -1.2990 0.7500 0.0000 C 0 0 -1.5549 3.6021 0.0000 O 0 0 -8.8087 9.9337 0.0000 O 0 0 -7.7590 12.0291 0.0000 O 0 0 -3.8912 5.2578 0.0000 C 0 0 1.2990 0.7500 0.0000 C 0 0 -9.0473 14.2875 0.0000 C 0 0 -5.1876 6.0124 0.0000 C 0 0 0.0000 1.5000 0.0000 C 0 0 -6.4780 8.2699 0.0000 C 0 0 -5.1824 7.5124 0.0000 C 0 0 -0.0031 -3.0008 0.0000 O 0 0 -9.0546 12.7867 0.0000 C 0 0 1 0 0 0 -2.5844 7.5034 0.0000 C 0 0 -2.5896 6.0034 0.0000 C 0 0 -3.8808 8.2579 0.0000 C 0 0 -1.0432 -3.5994 0.0000 C 0 0 -10.3567 12.0404 0.0000 C 0 0 -10.3612 10.8404 0.0000 C 0 0 2 12 1 0 3 6 3 0 4 11 3 0 5 18 1 0 6 5 1 0 7 10 1 0 8 1 1 0 9 1 1 0 10 13 2 0 11 19 1 0 12 22 1 0 13 8 1 0 14 1 2 0 15 2 2 0 16 2 1 0 17 9 1 0 18 21 2 0 19 25 1 0 20 17 1 0 21 13 1 0 22 23 1 0 23 20 2 0 24 7 1 0 25 16 1 6 26 27 1 0 27 17 2 0 28 26 2 0 29 24 1 0 30 25 1 0 31 30 1 0 7 5 2 0 28 23 1 0 M END > 120739 > Bioorg. Med. Chem. Lett. 13(20)-2003 3557-3560 > IMPDHII > 8.2218 $$$$ SciTegic07090714152D 31 36 0 0 0 0 999 V2000 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 -6.5147 1.5352 0.0000 C 0 0 -7.9421 1.0965 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 -5.2294 0.7541 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 -8.4202 -0.3261 0.0000 N 0 0 -3.9086 1.5029 0.0000 C 0 0 5.4950 -3.2941 0.0000 N 0 0 -8.8030 2.2919 0.0000 C 0 0 -6.4968 3.0302 0.0000 C 0 0 6.2469 -1.9962 0.0000 C 0 0 5.2449 -0.8800 0.0000 O 0 0 4.0282 -2.9800 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 -7.9134 3.5029 0.0000 C 0 0 -3.8898 2.9990 0.0000 C 0 0 -5.1933 3.7804 0.0000 C 0 0 -8.9217 -2.3308 0.0000 C 0 0 3.8911 1.5017 0.0000 O 0 0 -9.6915 -1.0434 0.0000 C 0 0 -7.6343 -1.5610 0.0000 C 0 0 3.8894 2.7017 0.0000 C 0 0 2 3 1 0 3 1 1 0 4 7 1 0 5 1 2 0 6 10 1 0 7 5 1 0 8 13 2 0 9 8 1 0 10 4 2 0 11 2 2 0 12 11 1 0 13 16 1 0 14 6 1 0 15 9 1 0 16 1 1 0 17 22 1 0 18 9 1 0 19 26 2 0 20 21 1 0 21 14 1 0 22 14 2 0 23 7 2 0 24 19 1 0 25 16 2 0 26 25 1 0 27 30 1 0 28 12 1 0 29 15 1 0 30 15 1 0 31 28 1 0 2 4 1 0 19 8 1 0 12 6 2 0 18 24 1 0 27 29 1 0 17 20 2 0 M END > 100915 > Bioorg. Med. Chem. Lett. 13(3)-2003 547-551 > IMPDHII > 8.2218 $$$$ SciTegic07090714152D 32 36 0 0 0 0 999 V2000 1.2990 -0.7500 0.0000 C 0 0 1.2990 0.7500 0.0000 N 0 0 0.0000 -1.5000 0.0000 N 0 0 -1.2990 0.7500 0.0000 N 0 0 -1.2990 -0.7500 0.0000 C 0 0 0.0000 1.5000 0.0000 C 0 0 -2.5847 -6.0040 0.0000 C 0 0 2.5987 -1.5004 0.0000 N 0 0 -2.5795 -7.5047 0.0000 C 0 0 -3.8863 -5.2585 0.0000 C 0 0 -3.3252 -9.7926 0.0000 N 0 0 -2.5972 -1.5031 0.0000 N 0 0 -3.8915 -3.7585 0.0000 C 0 0 -1.2883 -5.2495 0.0000 C 0 0 -1.8252 -9.7898 0.0000 C 0 0 -1.3644 -8.3623 0.0000 O 0 0 -3.7914 -8.3669 0.0000 C 0 0 -2.5951 -3.0039 0.0000 C 0 0 0.0000 3.0008 0.0000 C 0 0 5.1945 -3.0045 0.0000 O 0 0 -1.2935 -3.7495 0.0000 C 0 0 -5.1850 -6.0107 0.0000 O 0 0 3.8991 -0.7525 0.0000 C 0 0 2.5965 -3.0004 0.0000 C 0 0 3.8943 -3.7525 0.0000 C 0 0 5.1969 -1.5045 0.0000 C 0 0 1.2978 3.7529 0.0000 C 0 0 -1.3002 3.7488 0.0000 C 0 0 -6.2255 -5.4128 0.0000 C 0 0 1.2954 5.2529 0.0000 C 0 0 -1.3026 5.2488 0.0000 C 0 0 -0.0048 6.0009 0.0000 C 0 0 2 1 2 0 3 1 1 0 4 5 1 0 5 3 2 0 6 2 1 0 7 14 2 0 8 1 1 0 9 7 1 0 10 13 2 0 11 17 1 0 12 5 1 0 13 18 1 0 14 21 1 0 15 16 1 0 16 9 1 0 17 9 2 0 18 12 1 0 19 6 1 0 20 25 1 0 21 18 2 0 22 10 1 0 23 8 1 0 24 8 1 0 25 24 1 0 26 23 1 0 27 19 2 0 28 19 1 0 29 22 1 0 30 27 1 0 31 28 2 0 32 31 1 0 6 4 2 0 20 26 1 0 7 10 1 0 32 30 2 0 11 15 2 0 M END > 4764 > Bioorg. Med. Chem. Lett. 12(16)-2002 2137-2140 > IMPDHII > 6.7212 $$$$ SciTegic07090714152D 32 37 0 0 0 0 999 V2000 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 -6.5147 1.5352 0.0000 C 0 0 -7.9421 1.0965 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 -5.2294 0.7541 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 -8.4202 -0.3261 0.0000 N 0 0 -3.9086 1.5029 0.0000 C 0 0 5.4950 -3.2941 0.0000 N 0 0 -8.8030 2.2919 0.0000 C 0 0 -6.4968 3.0302 0.0000 C 0 0 6.2469 -1.9962 0.0000 C 0 0 5.2449 -0.8800 0.0000 O 0 0 4.0282 -2.9800 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 -7.9134 3.5029 0.0000 C 0 0 -3.8898 2.9990 0.0000 C 0 0 -5.1933 3.7804 0.0000 C 0 0 3.8911 1.5017 0.0000 O 0 0 -9.8050 -0.8560 0.0000 C 0 0 -7.4537 -1.4576 0.0000 C 0 0 3.8894 2.7017 0.0000 C 0 0 -9.7096 -2.3530 0.0000 C 0 0 -8.2564 -2.7248 0.0000 C 0 0 2 3 1 0 3 1 1 0 4 7 1 0 5 1 2 0 6 10 1 0 7 5 1 0 8 13 2 0 9 8 1 0 10 4 2 0 11 2 2 0 12 11 1 0 13 16 1 0 14 6 1 0 15 9 1 0 16 1 1 0 17 22 1 0 18 9 1 0 19 26 2 0 20 21 1 0 21 14 1 0 22 14 2 0 23 7 2 0 24 19 1 0 25 16 2 0 26 25 1 0 27 12 1 0 28 15 1 0 29 15 1 0 30 27 1 0 31 28 1 0 32 29 1 0 2 4 1 0 19 8 1 0 12 6 2 0 18 24 1 0 32 31 1 0 17 20 2 0 M END > 100916 > Bioorg. Med. Chem. Lett. 13(3)-2003 547-551 > IMPDHII > 7.8861 $$$$ SciTegic07090714152D 33 38 0 0 0 0 999 V2000 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -6.5182 1.5178 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 -7.8188 0.7764 0.0000 C 0 0 -5.2260 0.7619 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 -7.8272 -0.7243 0.0000 N 0 0 -3.9086 1.5029 0.0000 C 0 0 5.4950 -3.2941 0.0000 N 0 0 -6.5098 3.0151 0.0000 C 0 0 6.2469 -1.9962 0.0000 C 0 0 5.2449 -0.8800 0.0000 O 0 0 4.0282 -2.9800 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 -7.8021 3.7709 0.0000 O 0 0 -3.8988 3.0005 0.0000 C 0 0 -5.2093 3.7564 0.0000 C 0 0 -9.1110 1.5323 0.0000 C 0 0 3.8911 1.5017 0.0000 O 0 0 -9.1027 3.0295 0.0000 C 0 0 -9.0441 -1.5794 0.0000 C 0 0 -6.6171 -1.5889 0.0000 C 0 0 3.8894 2.7017 0.0000 C 0 0 -7.0862 -3.0137 0.0000 C 0 0 -8.5862 -3.0078 0.0000 C 0 0 2 3 1 0 3 1 1 0 4 8 1 0 5 11 2 0 6 1 2 0 7 9 1 0 8 6 1 0 9 4 2 0 10 5 1 0 11 16 1 0 12 2 2 0 13 12 1 0 14 7 1 0 15 10 1 0 16 1 1 0 17 21 1 0 18 25 2 0 19 20 1 0 20 14 1 0 21 14 2 0 22 8 2 0 23 18 1 0 24 16 2 0 25 24 1 0 26 10 1 0 27 13 1 0 28 23 1 0 29 15 1 0 30 15 1 0 31 27 1 0 32 30 1 0 33 29 1 0 2 4 1 0 18 5 1 0 13 7 2 0 28 26 1 0 32 33 1 0 17 19 2 0 M END > 100903 > Bioorg. Med. Chem. Lett. 13(3)-2003 547-551 > IMPDHII > 7.4815 $$$$ SciTegic07090714152D 33 38 0 0 0 0 999 V2000 -2.6111 0.7486 0.0000 C 0 0 0.0000 0.7486 0.0000 C 0 0 -1.2964 1.4973 0.0000 N 0 0 0.0000 -0.7486 0.0000 C 0 0 -2.6111 -0.7486 0.0000 C 0 0 2.5929 -0.7486 0.0000 C 0 0 -1.2964 -1.4973 0.0000 C 0 0 -6.5147 1.5352 0.0000 C 0 0 -7.9421 1.0965 0.0000 C 0 0 1.2964 -1.4973 0.0000 C 0 0 1.2964 1.4973 0.0000 C 0 0 2.5929 0.7486 0.0000 C 0 0 -5.2294 0.7541 0.0000 C 0 0 3.8926 -1.4990 0.0000 C 0 0 -8.4202 -0.3261 0.0000 N 0 0 -3.9086 1.5029 0.0000 C 0 0 5.4950 -3.2941 0.0000 N 0 0 -8.8030 2.2919 0.0000 C 0 0 -6.4968 3.0302 0.0000 C 0 0 6.2469 -1.9962 0.0000 C 0 0 5.2449 -0.8800 0.0000 O 0 0 4.0282 -2.9800 0.0000 C 0 0 -1.2928 -2.6973 0.0000 O 0 0 -7.9134 3.5029 0.0000 C 0 0 -3.8898 2.9990 0.0000 C 0 0 -5.1933 3.7804 0.0000 C 0 0 -9.1677 -3.2283 0.0000 O 0 0 3.8911 1.5017 0.0000 O 0 0 -9.8614 -0.7246 0.0000 C 0 0 -7.3463 -1.3756 0.0000 C 0 0 -7.7221 -2.8278 0.0000 C 0 0 -10.2373 -2.1767 0.0000 C 0 0 3.8894 2.7017 0.0000 C 0 0 2 3 1 0 3 1 1 0 4 7 1 0 5 1 2 0 6 10 1 0 7 5 1 0 8 13 2 0 9 8 1 0 10 4 2 0 11 2 2 0 12 11 1 0 13 16 1 0 14 6 1 0 15 9 1 0 16 1 1 0 17 22 1 0 18 9 1 0 19 26 2 0 20 21 1 0 21 14 1 0 22 14 2 0 23 7 2 0 24 19 1 0 25 16 2 0 26 25 1 0 27 31 1 0 28 12 1 0 29 15 1 0 30 15 1 0 31 30 1 0 32 29 1 0 33 28 1 0 2 4 1 0 19 8 1 0 12 6 2 0 18 24 1 0 27 32 1 0 17 20 2 0 M END > 100917 > Bioorg. Med. Chem. Lett. 13(3)-2003 547-551 > IMPDHII > 7.6990 $$$$